Co-Mepiryl

Combination Therapy for Type 2 Diabetes Management

Co-Mepiryl is an oral antidiabetic medication used to help control blood sugar levels in individuals with Type 2 Diabetes Mellitus. It combines Glimepiride, which stimulates insulin production, and Metformin, which improves insulin sensitivity and reduces glucose production in the liver. This dual-action formula helps regulate blood sugar levels effectively, reducing the risk of diabetes-related complications.

Active Ingredients

• Glimepiride – A sulfonylurea that stimulates the pancreas to release more insulin.
• Metformin – A biguanide that reduces glucose production in the liver and improves insulin sensitivity.

Indications (Uses)

Co-Mepiryl is prescribed for:

• Managing Type 2 Diabetes Mellitus when diet and exercise alone are insufficient.
• Combination therapy for individuals requiring dual treatment to control blood sugar levels.
• Reducing the risk of diabetes-related complications such as heart disease and kidney problems.

Dosage and Administration

• Adults: Take one tablet once or twice daily, as prescribed by a doctor.
• Take with food to reduce the risk of stomach upset.
• Swallow whole with water—do not crush or chew.
• Follow a balanced diet and exercise plan for the best results.

Precautions and Warnings

• Not for use in Type 1 Diabetes or diabetic ketoacidosis.
• Monitor blood sugar levels regularly to avoid hypoglycemia or hyperglycemia.
• May cause low blood sugar (hypoglycemia), especially if meals are skipped.
• Use with caution in patients with kidney, liver, or heart conditions.
• Avoid excessive alcohol consumption, as it may increase the risk of lactic acidosis.
• Pregnant or breastfeeding women should consult a doctor before use.

Possible Side Effects

Co-Mepiryl is generally well-tolerated, but some users may experience:

• Hypoglycemia (low blood sugar) – Sweating, dizziness, hunger, shakiness.
• Nausea, vomiting, or diarrhea – Common but usually temporary.
• Metallic taste in the mouth.
• Weight gain (due to Glimepiride).
• Lactic acidosis (rare but serious) – Seek medical attention if you experience muscle pain, trouble breathing, or unusual fatigue.

Storage Instructions

• Store in a cool, dry place, away from direct sunlight.
• Keep out of reach of children.
• Do not use after the expiry date.