Overview
Everolimus 10mg is a potent oral medication belonging to the class of drugs known as kinase inhibitors or mTOR (mammalian target of rapamycin) inhibitors. It is primarily prescribed for the treatment of various types of cancers and certain non-cancerous tumors. Manufactured by Novartis, it is most commonly known by the brand names Afinitor and Votubia.
Indications and Uses
Everolimus 10mg is clinically indicated for several conditions, including:
- Advanced Breast Cancer: Used in combination with exemestane for hormone receptor-positive, HER2-negative advanced breast cancer in postmenopausal women.
- Renal Cell Carcinoma (RCC): For the treatment of advanced kidney cancer when other treatments (VEGF-targeted therapy) have not been successful.
- Neuroendocrine Tumors (NET): For progressive tumors of pancreatic, gastrointestinal, or lung origin.
- Tuberous Sclerosis Complex (TSC): To treat subependymal giant cell astrocytoma (SEGA) and renal angiomyolipoma.
How Everolimus Works
Everolimus works by blocking the mTOR protein. This protein is a central regulator of cell division and the growth of blood vessels. By inhibiting this protein, Everolimus helps to slow down the growth and spread of cancer cells and reduces the blood supply to tumors.
Dosage and Administration
This medication is taken orally, typically once a day at the same time. It should be swallowed whole with a glass of water and can be taken with or without food, but consistency is key. Always follow the specific dosage instructions provided by your oncologist or healthcare provider.
Storage and Handling
- Store below 30°C.
- Keep the tablets in the original blister pack to protect them from light and moisture.
- Keep out of reach of children.
For further clinical guidance or to verify availability, you can consult with a GoMed pharmacist.