Ibasunate Softgel - 9 Capsules
Overview
Ibasunate Softgel Capsules are an effective treatment for uncomplicated malaria, containing the active ingredients dihydroartemisinin and piperaquine. These ingredients work together to target and eliminate the Plasmodium parasites that cause malaria.
Key Ingredients
- Dihydroartemisinin (40mg): Rapidly absorbed and works by disrupting the parasite's cell membrane and protein synthesis.
- Piperaquine Phosphate (320mg): Interferes with the parasite's food vacuole, leading to its death. It has a longer half-life, ensuring prolonged efficacy against malaria.
Uses
- Malaria Treatment: Ibasunate is specifically indicated for the treatment of uncomplicated Plasmodium falciparum malaria. It is administered over three days to ensure complete eradication of the parasite.
Dosage and Administration
- Adults and Children: The dosage varies based on body weight and should be taken once daily for three days. For example, adults weighing 60-80 kg typically take four tablets daily for three days. It is crucial to follow the exact dosage prescribed by a healthcare provider.
Side Effects
Common side effects may include:
- Nausea and vomiting
- Dizziness
- Headache
- Abdominal discomfort
Serious side effects are rare but can include allergic reactions, changes in heart rhythm (QT prolongation), and severe skin reactions.
Precautions
- Pregnancy and Breastfeeding: There is limited data on the use of Ibasunate during pregnancy and breastfeeding. It is not recommended during the first trimester of pregnancy due to potential risks. Consult your doctor before use if you are pregnant or breastfeeding.
- Drug Interactions: Ibasunate can interact with other medications, especially those affecting the liver enzymes CYP3A4 and CYP2C19. Inform your healthcare provider of all medications you are taking.
Storage
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.