What is Tolvact-15?
Tolvact-15 is a medication containing Tolvaptan 15mg, manufactured by Johnlee Pharmaceuticals. It belongs to a class of drugs known as selective vasopressin V2-receptor antagonists. This medication is primarily used to manage low sodium levels in the blood, a condition called hyponatremia.
How Tolvact-15 Works
Tolvaptan works by blocking the action of vasopressin, a hormone that regulates water balance in the body. By inhibiting this hormone, Tolvact-15 helps the kidneys increase water excretion without losing significant amounts of electrolytes like sodium. This process helps to naturally raise and stabilize sodium levels in the blood.
Common Uses
Tolvact-15 is typically indicated for treating clinically significant hyponatremia associated with:
- Congestive heart failure
- Liver cirrhosis
- Syndrome of Inappropriate Antidiuretic Hormone (SIADH)
- Autosomal Dominant Polycystic Kidney Disease (ADPKD) in some clinical settings.
Important Safety Information
Due to the risk of rapid sodium correction, which can lead to serious neurological complications, treatment with Tolvact-15 is usually initiated or re-initiated in a hospital setting where serum sodium can be closely monitored.
Always consult with a healthcare professional or a GoMed pharmacist before starting this medication. Long-term use may also require monitoring for potential liver injury.