Metaprim 25mg Tablets (Pyrimethamine)
Metaprim is a brand of Pyrimethamine (25mg) tablets manufactured by SKG-Pharma Limited in Nigeria. It is a dihydrofolate reductase inhibitor primarily used to treat certain parasitic infections.
What is Metaprim used for?
In the Nigerian medical context, Metaprim is most commonly prescribed for:
- Toxoplasmosis Treatment: When used alongside a sulfonamide (such as sulfadiazine), it is effective in clearing toxoplasma infections.
- Malaria Management: While historically an antimalarial, it is now primarily used for prophylaxis or as part of specific clinical regimens. It is rarely used as a standalone treatment for malaria due to widespread resistance.
Note: Metaprim is often confused with "SP" combination drugs (Sulfadoxine/Pyrimethamine). However, Metaprim contains only Pyrimethamine.
Dosage and Administration
The dosage of Metaprim depends on the condition being treated and the patient's age or weight.
- For Toxoplasmosis: Typically involves a higher loading dose followed by a maintenance period.
- How to take: Swallow the tablets with a glass of water, preferably after a meal to minimize stomach upset.
Always follow the specific instructions provided by your doctor or GoMed pharmacist.
Side Effects
Common side effects may include:
- Nausea or vomiting
- Loss of appetite
- Skin rash
- Dizziness
If you experience a severe allergic reaction or persistent vomiting, seek medical attention immediately.
Safety and Pregnancy
Can a pregnant woman take Metaprim? Metaprim should generally be avoided during the first trimester of pregnancy. It may be used in later stages for specific indications under strict medical supervision. Always consult a healthcare professional before use.
Storage
Store in a cool, dry place away from direct sunlight and keep out of reach of children.