What is Philoquin Quinine Dihydrochloride Injection?
Philoquin is a potent antimalarial medication containing Quinine Dihydrochloride (600mg in each 2ml ampoule). It belongs to the cinchona alkaloid class and is primarily used for the emergency treatment of severe or complicated malaria caused by Plasmodium falciparum. This includes cases where the patient is unable to take oral medications or when the infection has progressed to cerebral malaria.
Indications and Use in Nigeria
In the Nigerian healthcare context, Philoquin is a critical intervention for acute malaria cases. It is often administered in hospital settings when rapid parasite clearance is necessary to prevent complications. Due to its potency and specific administration requirements, it is strictly a prescription-only medication and should only be handled by trained healthcare professionals.
Administration and Safety Note
Safety is paramount with injectable quinine. Philoquin must be diluted in a 5% glucose or isotonic solution and administered via slow intravenous (IV) infusion. It should never be given as a bolus IV injection, as this can lead to severe cardiotoxicity. In certain clinical situations, it may be administered via deep intramuscular (IM) injection by a medical professional.
Manufacturer and Quality Information
Philoquin is manufactured by Hubei Tianyao Pharmaceutical Co. Ltd. (a subsidiary of the Tianjin KingYork Group) and is distributed in Nigeria by A-Nwaeze Pharmaceutical Company Limited. The product is registered with NAFDAC under number A4-1237. As with all injectable medications, ensure the seal is intact and the solution is clear before use.