Reludrine 100mg (Proguanil) for Malaria Prevention

Reludrine is a pharmaceutical antimalarial agent used primarily for malaria prophylaxis (prevention). Each tablet contains 100mg of Proguanil Hydrochloride, a biguanide derivative that helps protect individuals from malaria infections, especially when traveling to malaria-endemic regions like Nigeria.

How Reludrine Works

The active ingredient, Proguanil, works by inhibiting the dihydrofolate reductase enzyme of the malaria parasite. This action stops the parasite from synthesizing DNA, preventing it from reproducing in the bloodstream. It is effective against Plasmodium falciparum and Plasmodium vivax.

Usage and Prophylaxis

Reludrine is most effective when taken daily at the same time. For travelers, it is usually recommended to start the medication 24 to 48 hours before entering a malaria-prone area and to continue taking it for 4 weeks after leaving the area.

Guidance for Use in Nigeria

In Nigeria, Reludrine is marketed by Reals Pharmaceutical Limited and manufactured by McW Healthcare Pvt Ltd. It is often referred to locally as a "sachet" of Reludrine, which typically contains a strip of 10 tablets.

While Reludrine is a trusted medication for prevention, it is not typically used as a standalone treatment for active malaria cases. For treatment of an ongoing infection, other combination therapies are usually required.

Consultation

It is important to use antimalarials correctly to ensure protection. If you have questions about the dosage or suitability of Reludrine for your travel plans, you can contact a GoMed pharmacist for professional advice.