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PEFLOMED TABLETS

Overview

Peflomed Tablets are an antibiotic medication containing pefloxacin, a fluoroquinolone that is effective against a wide range of bacterial infections. This medication is commonly used to treat typhoid fever, soft tissue infections, gastrointestinal infections, genito-urinary infections, and bone and joint infections.

Benefits of Peflomed Tablets

Broad-Spectrum Antibiotic

Peflomed Tablets are effective in treating various bacterial infections due to their broad-spectrum activity. They inhibit bacterial DNA replication and transcription, which helps in eliminating the infection.

Effective Against Multiple Infections

Peflomed is proven effective in the treatment of:

Typhoid fever
Soft tissue infections
Gastrointestinal infections
Genito-urinary infections
Bone and joint infections

Composition

Each Peflomed Tablet contains:

Pefloxacin Mesilate 400 mg

Dosage and Administration

Oral Administration: The usual dose is 400 mg twice daily (morning and evening). It is recommended to take the tablets with meals to avoid gastrointestinal disturbances.
Intravenous Infusion: 400 mg in 100 ml of 5% dextrose solution, administered slowly over one hour twice daily.

Side Effects

Common side effects of Peflomed Tablets may include:

Gastrointestinal issues: nausea, diarrhea, vomiting, dyspepsia, and abdominal pain
Central nervous system effects: dizziness, headache, tiredness, confusion, and convulsions
Hypersensitivity reactions: skin rashes and pruritus
Other reactions: joint pain, photosensitivity, and thrombocytopenia

Precautions

Sunlight Exposure: Avoid exposure to sunlight and ultraviolet radiation during treatment to prevent photosensitivity reactions.
Hepatic Insufficiency: Dosage adjustment is required for patients with severe hepatic insufficiency.
Contraindications: Not recommended for use in children and growing adolescents, pregnant women, nursing mothers, and patients with glucose-6-phosphate dehydrogenase deficiency.

Interactions

Antacids can interfere with the absorption of Peflomed, leading to lower serum and urine levels. Therefore, concurrent use of antacids and Peflomed should be avoided.