Dolutegravir, Lamivudine and Tenofovir

Dolutegravir, Lamivudine, and Tenofovir

Overview

Dolutegravir, Lamivudine, and Tenofovir are antiretroviral medications used in combination to treat HIV-1 infection. This combination is effective in reducing the viral load in the body, helping to manage HIV infection and prevent its progression to AIDS.

Product Details

• Form: Tablets
• Dosage: Typically one tablet taken orally once a day

Uses

This combination is used primarily for:

• HIV-1 Treatment: Helps in reducing the amount of HIV in the body and maintaining a low viral load, which is crucial for managing HIV infection.
• Prevention of HIV Transmission: By reducing the viral load, it also helps in lowering the risk of transmitting the virus to others.

Health Benefits

The combination of these three drugs offers several benefits:

• Viral Suppression: Helps in achieving and maintaining an undetectable viral load.
• Immune System Support: Assists in maintaining a healthier immune system by controlling the virus.
• Resistance Management: Reduces the likelihood of developing drug-resistant strains of HIV due to its potent triple-drug regimen.

Usage Instructions

• Administration: Take one tablet once daily, with or without food.
• Missed Dose: If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. Do not take two doses at once.
• Consistency: It is important to take the medication at the same time every day to maintain an effective level of the drug in your body.

Precautions

• Pregnancy: This medication may cause birth defects if taken during pregnancy. Effective contraception is required for women of childbearing age.
• Breastfeeding: Women with HIV or AIDS should not breastfeed, as the virus can be transmitted to the baby through breast milk.
• Liver and Kidney Health: Regular monitoring of liver and kidney function is necessary due to potential side effects.
• Drug Interactions: Inform your doctor about any other medications you are taking, as this combination can interact with other drugs, including certain antacids and supplements.

Side Effects

Common side effects may include:

• Headache and Tiredness
• Nausea and Diarrhea
• Insomnia
• Rash and Changes in Body Fat Distribution

Serious side effects can include:

• Lactic Acidosis: A rare but serious condition that can occur due to a buildup of lactic acid in the blood.
• Liver Problems: Signs include upper stomach pain, loss of appetite, dark urine, and jaundice (yellowing of the skin or eyes).

Regular medical check-ups and blood tests are crucial to monitor for any adverse effects and to ensure the medication is working effectively.

Storage

• Conditions: Store at room temperature away from moisture and heat. Keep the medication in its original container and tightly closed when not in use.

This combination therapy is a crucial component in the management of HIV-1 infection, offering significant benefits in maintaining health and preventing the progression of the disease.