GLUCOVANCE 500MG/2.5MG X 30 TABS

Glucovance 500mg/2.5mg – Combination Oral Anti-Diabetic Therapy (30 Tablets)

Glucovance 500mg/2.5mg combines two effective anti-diabetic agents—Metformin Hydrochloride (500mg) and Glibenclamide (2.5mg)—to help manage type 2 diabetes mellitus in adults. This dual-action formulation improves insulin sensitivity and promotes insulin release from the pancreas, offering comprehensive blood sugar control.

Ingredients

• Active Ingredients:
  • Metformin Hydrochloride – 500mg
  • Glibenclamide – 2.5mg
• Excipients: May include povidone, magnesium stearate, cellulose, and film-coating agents (refer to packaging insert for full details).

Key Benefits

• Combines two complementary mechanisms for effective blood sugar control
• Improves insulin sensitivity and reduces hepatic glucose production
• Stimulates the pancreas to release more insulin
• May reduce the need for higher doses of individual medications

Uses

Glucovance is indicated for:

• Management of type 2 diabetes mellitus in adults
• Patients whose blood sugar levels are not adequately controlled with diet and exercise alone
• As an adjunct to diet and lifestyle changes to improve glycemic control

Dosage and Administration

• Dosage must be individualized based on the patient’s response and medical advice
• Typically taken once or twice daily with meals to reduce gastrointestinal side effects
• Do not crush or chew tablets; swallow whole with water

Warnings and Precautions

• Not recommended for type 1 diabetes or diabetic ketoacidosis
• Use with caution in elderly patients and those with renal or hepatic impairment
• May cause hypoglycemia, especially when taken without food or with other anti-diabetic medications
• Avoid excessive alcohol consumption while on this medication

Possible Side Effects

• Nausea, vomiting, or stomach upset (especially at the beginning of treatment)
• Low blood sugar (hypoglycemia) symptoms such as dizziness, sweating, or shaking
• Rarely, lactic acidosis—a serious condition requiring urgent medical attention

Storage Instructions

• Store in a cool, dry place below 30°C
• Keep out of reach of children
• Do not use after the expiry date on the package

Note: Always use this medication under the supervision of a qualified healthcare provider. Regular monitoring of blood sugar levels is essential.