Celebrex (Celecoxib) Capsules

Nonsteroidal Anti-Inflammatory Drug (NSAID) for Pain and Inflammation

Celebrex is a prescription medication containing celecoxib, a nonsteroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2). It is commonly used to relieve pain and inflammation associated with various conditions.

Indications

• Osteoarthritis: Alleviates joint pain and stiffness.

• Rheumatoid Arthritis: Reduces inflammation and pain in the joints.

• Ankylosing Spondylitis: Eases symptoms of spinal arthritis.

• Acute Pain: Manages short-term pain, such as postoperative discomfort.

• Primary Dysmenorrhea: Relieves menstrual pain.

Dosage and Administration

• Osteoarthritis: 200 mg once daily or 100 mg twice daily.

• Rheumatoid Arthritis: 100–200 mg twice daily.

• Ankylosing Spondylitis: 200 mg daily, either as a single dose or divided into two doses.

• Acute Pain and Primary Dysmenorrhea: Initial dose of 400 mg, followed by an additional 200 mg if needed on the first day; then 200 mg twice daily as required.

Note: Dosage should be individualized based on patient needs and response. Always follow the prescribing physician's instructions.

Contraindications

• Known hypersensitivity to celecoxib or any component of the formulation.

• Allergy to sulfonamides.

• History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.

• Use in the setting of coronary artery bypass graft (CABG) surgery.

Warnings and Precautions

• Cardiovascular Risk: May increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke.

• Gastrointestinal Risk: Increased risk of gastrointestinal bleeding, ulceration, and perforation.

• Renal Effects: Caution in patients with impaired renal function.

• Hepatic Effects: Monitor liver function in patients with hepatic impairment.

Side Effects

• Common: Abdominal pain, diarrhea, dyspepsia, flatulence, edema.

• Serious: Cardiovascular events, gastrointestinal bleeding, hepatotoxicity, renal toxicity, serious skin reactions.

Seek immediate medical attention if serious side effects occur.

Drug Interactions

• May interact with anticoagulants, other NSAIDs, ACE inhibitors, diuretics, and lithium.

• Inform your healthcare provider of all medications and supplements you are taking.

Use in Specific Populations

• Pregnancy: Use is not recommended, especially in the third trimester.

• Lactation: Not recommended; consult your healthcare provider.

• Pediatric Use: Safety and efficacy have not been established in patients under 18 years of age.

Storage

• Store at room temperature, away from moisture and heat.

• Keep out of reach of children.

Note: This information is a summary and does not contain all possible information about this product. Consult your healthcare provider for personalized medical advice.