Citicoline Sodium 500mg is a brain chemical that occurs naturally in the body. It's in dietary supplements in the US, but was originally a prescription drug in Japan. Citicoline seems to increase a brain chemical called phosphatidylcholine. Citicoline might also increase the amounts of other chemicals that send messages in the brain. It was originally used as a drug to help improve memory and brain function after a stroke. People use citicoline for age-related decline in memory and thinking, glaucoma, stroke, Alzheimer disease, bipolar disorder, depression, and many other conditions, but there is no good scientific research to support most of these uses. Don't confuse citicoline with choline or phosphatidylcholine. These are not the same.