Promethazine Injection 50mg/2ml – Antihistamine and Antiemetic

Promethazine Injection 50mg/2ml is a prescription-only medication used for the treatment of allergic reactions, nausea, vomiting, motion sickness, and as a sedative or adjunct to anesthesia. It belongs to the phenothiazine class of antihistamines and offers rapid relief when oral administration is not feasible.

Product Details

• Generic Name: Promethazine Hydrochloride
• Strength: 50mg per 2ml (25mg/ml)
• Form: Injection
• Route of Administration: Intramuscular (IM) or slow Intravenous (IV) injection
• Pack Size: 2ml ampoule (pack quantity may vary)
• Drug Class: Antihistamine / Phenothiazine derivative

Composition

Each 2ml ampoule contains:

• Promethazine Hydrochloride – 50mg
• Water for injection and suitable preservatives

Uses and Indications

Promethazine Injection is indicated for the management of:

• Severe allergic reactions, including anaphylaxis (adjunctive use)
• Nausea and vomiting (including post-operative)
• Motion sickness
• Pre-operative sedation
• Adjunct in pain management and post-anesthesia recovery

Key Benefits

• Rapid onset of action for acute conditions
• Multiple clinical uses – antiemetic, sedative, and antihistamine
• Useful when oral medications cannot be administered
• Widely used in emergency and perioperative settings

How to Use

Promethazine Injection should be administered by a healthcare professional. It can be given intramuscularly or by slow intravenous injection. Dosage depends on the indication, patient’s age, and response to therapy. Avoid intra-arterial injection or subcutaneous use due to risk of tissue damage.

Safety Information

• Use only under medical supervision
• May cause drowsiness, dizziness, or hypotension
• Contraindicated in children under 2 years of age due to risk of respiratory depression
• Not recommended in patients with severe CNS depression, coma, or known hypersensitivity to promethazine
• Use with caution in the elderly and those with liver or cardiovascular conditions

Storage Instructions

Store below 25°C. Protect from light and freezing. Keep out of reach of children. Do not use if the solution appears cloudy or contains particles.