Trijardy XR 25mg/5mg/1000mg Tablets

Overview

Trijardy XR combines three diabetes medications—empagliflozin, linagliptin, and metformin hydrochloride—into a single tablet. This combination helps manage blood sugar levels in adults with type 2 diabetes and can also reduce the risk of cardiovascular death in those with established heart disease.

Benefits

• Improves Glycemic Control: Helps lower blood sugar levels in adults with type 2 diabetes.
• Reduces Cardiovascular Risk: Empagliflozin can reduce the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease.
• Convenient Combination: Combines three medications into one tablet, simplifying the treatment regimen.

Key Ingredients

• Empagliflozin (25mg): A sodium-glucose co-transporter 2 (SGLT2) inhibitor that helps remove excess glucose through urine.
• Linagliptin (5mg): A dipeptidyl peptidase-4 (DPP-4) inhibitor that increases insulin release and decreases glucagon levels in the blood.
• Metformin (1000mg): A biguanide that reduces glucose production in the liver and improves insulin sensitivity.

How to Use

1. Dosage: Take one tablet daily in the morning with a meal.
2. Administration: Swallow the tablet whole; do not split, crush, or chew.
3. Missed Dose: If you miss a dose, take it as soon as you remember. Skip the missed dose if it is almost time for your next one. Do not take two doses at once.

Precautions

• Kidney Function: Monitor kidney function regularly, especially in elderly patients.
• Avoid Alcohol: Excessive alcohol can increase the risk of lactic acidosis.
• Hydration: Maintain proper hydration to avoid dehydration, especially if you have low blood pressure or are taking diuretics.
• Avoid During Pregnancy and Breastfeeding: Not recommended during the second and third trimesters of pregnancy or while breastfeeding.

Side Effects

Common side effects may include:

• Headache
• Nasal congestion
• Diarrhea or constipation
• Upper respiratory tract infections

Serious side effects requiring immediate medical attention:

• Severe joint pain
• Signs of lactic acidosis (e.g., unusual muscle pain, trouble breathing)
• Severe allergic reactions (e.g., rash, swelling)
• Ketoacidosis (nausea, vomiting, abdominal pain)

Interactions

• Nitrates: Avoid using with medications containing nitrates.
• Diuretics: Increased risk of dehydration.
• Insulin: May need dosage adjustment when taken with insulin to prevent hypoglycemia.
• Alcohol: Can increase the risk of lactic acidosis.

Storage

• Store at room temperature away from moisture and heat.
• Keep out of reach of children.

Trijardy XR is an effective and convenient option for managing type 2 diabetes and reducing cardiovascular risks. Always follow your doctor's instructions and regularly monitor your health parameters to ensure the best results.