Premarin (Conjugated Estrogens) Tablets

Product Overview

Premarin tablets contain conjugated estrogens, a mixture of estrogen hormones derived from natural sources. Estrogen is a female sex hormone essential for various bodily functions, including the regulation of the menstrual cycle and reproductive system.

Indications

Premarin is prescribed for:

• Menopausal Symptoms: Alleviating moderate to severe hot flashes, night sweats, and vaginal dryness associated with menopause.

• Vulvar and Vaginal Atrophy: Treating changes in and around the vagina due to menopause.

• Osteoporosis Prevention: Reducing the risk of osteoporosis (bone loss) in postmenopausal women.

• Estrogen Replacement: Addressing estrogen deficiency due to ovarian failure or other conditions.

Dosage and Administration

• Dosage: The dosage varies based on the condition being treated. For menopausal symptoms, a common starting dose is 0.3 mg to 0.625 mg once daily. For osteoporosis prevention, the dose may range from 0.3 mg to 0.625 mg daily. Always follow your healthcare provider's instructions.

• Administration: Take the tablet orally at the same time each day, with or without food. Swallow the tablet whole with water.

Precautions

• Endometrial Cancer: Estrogen-alone therapy increases the risk of endometrial cancer in women with a uterus. Adding a progestin reduces this risk.

• Cardiovascular Disorders and Dementia: Estrogen therapy may increase the risk of heart attack, stroke, and dementia. Use the lowest effective dose for the shortest duration consistent with treatment goals.

• Breast Cancer: Estrogen therapy may increase the risk of breast cancer. Regular breast examinations and mammograms are recommended.

• Blood Clots: There is an increased risk of deep vein thrombosis (DVT) and pulmonary embolism (PE) with estrogen use.

Side Effects

Common side effects may include:

• Headache

• Breast Pain

• Irregular Vaginal Bleeding or Spotting

• Stomach/Abdominal Cramps and Bloating

• Nausea and Vomiting

• Hair Loss

• Fluid Retention

• Vaginal Yeast Infection

Seek immediate medical attention if you experience signs of a serious allergic reaction, such as rash, itching/swelling, severe dizziness, or trouble breathing.

Storage

• Temperature: Store at room temperature, away from moisture and heat.

• Keep Out of Reach of Children: Ensure that the medication is stored safely away from children.

Note: Always use Premarin as prescribed by a healthcare professional. Discuss your medical history and any current medications with your doctor before starting treatment to ensure it is safe and appropriate for you.