GVITHER PLUS 80/480 X 6 contains Artemether and lumenfantrine as active ingredient which works by interacting with heme to kill malaria parasites. It is advised that before using Gvither Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal SUPPLEMENTS, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug And should be Taken as directed by the doctor.