What is Macleods Isoniazid 300mg?
Macleods Isoniazid 300mg (also known as INH) is a primary antibiotic used for the treatment and prevention of tuberculosis (TB). It belongs to the hydrazide class of medicines and works by stopping the growth of the bacteria that cause TB.
In Nigeria, this medication is a core part of the National Tuberculosis and Leprosy Control Programme (NTBLCP) guidelines. It is often used for TB Preventive Treatment (TPT) to stop latent infections from becoming active.
Key Uses & Benefits
- Active TB Treatment: Usually taken with other medications (like Rifampicin) as part of a multi-drug regimen.
- TB Prevention: Used for individuals exposed to TB or those with latent infections.
- WHO Prequalified: Manufactured by Macleods Pharmaceuticals, a trusted global provider of TB medicines.
How to Take Isoniazid 300mg
For best results, take this medicine on an empty stomach, either 1 hour before or 2 hours after meals. It is important to take it at the same time every day to maintain a steady level in your system.
Complete the full course of treatment as prescribed by your doctor. Stopping early can lead to the bacteria becoming resistant to the drug.
Side Effects and Precautions
Common side effects include nausea, loss of appetite, and fatigue. Some people may experience numbness or tingling in the hands and feet (peripheral neuropathy). To prevent this, your doctor may prescribe Vitamin B6 (Pyridoxine) to take alongside your Isoniazid.
Important: Avoid drinking alcohol while on this medication, as it increases the risk of liver irritation. If you notice yellowing of the eyes or dark urine, contact your healthcare provider immediately.
If you have questions about TB treatment or need guidance, you can speak with a GoMed pharmacist.